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In summary current evidence suggests that bone targeted agen
2019-04-19
In summary, current evidence suggests that bone-targeted agents reduce morbidity from metastatic disease to bone, and potentially improve quality of life in patients with metastatic breast cancer. As there are costs and potential adverse effects associated with these agents, care should be taken in
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br Conflict of Interest br
2019-04-19
Conflict of Interest Acknowledgments Introduction Human ether-a-go-go-related gene (hERG) encodes the alpha subunit of the rapidly-activating delayed-rectifier K+ channel, which plays a pivotal role in repolarization of cardiac action potentials (APs) [1]. Most of mutant hERG proteins causi
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Como es l gico hay un personaje que hace
2019-04-19
Como es lógico, hay un personaje que hace de contrapunto butein esa posición y que por ello mismo la vuelve, por efecto de una diférance (Derrida 1972b), mucho más significativa. Lily, la mujer de Nicolás, no comprende ni lo más mínimo la fascinación que ejerce sobre su marido esa novela. La razón e
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The Cl HCO anion exchanger AE
2019-04-19
The Cl−/HCO3− anion exchanger 2 (AE2) is found on cholangiocytes and regulates intracellular pH homeostasis and stimulates bicarbonate secretion. Previous reports have revealed that PBC patients show decreased biliary AE2 expression, and researchers hypothesized that this decrease in AE2 BMS-354825
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In a letter to the
2019-04-18
In a letter to the editor of , Dasanu reported the case of a 55-yr-old male diagnosed with t(11;14)+ IgG-lambda MM, who presented with enlarged lymph nodes six years later. Biopsy was consistent with CD5-negative MCL. In 1999, Yamaguchi conducted clonal relationship analysis on myeloma and lymphoma
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br Methods As we were not privy to the
2019-04-18
Methods As we were not privy to the median year of enrolment, for all selected studies, the mean enrolment year ([start of enrolment+end of enrolment]/2) was calculated. If these dates were unavailable, the corresponding authors or sponsoring companies were contacted. When all methods to gather t
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br Hybrid approach It is still
2019-04-18
Hybrid approach It is still not certain whether a single or a staged approach is safer and more effective. Natale et al. [31] performed a combined closed-chest epicardial monopolar radiofrequency ablation through a transabdominal transdiaphragmatic single port and catheter-based transseptal endoc
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Effect of atorvastatin in modulation
2019-04-18
Effect of atorvastatin in modulation and protection of cardiomyocyte ischemia and inflammatory phenomena (identified as a decline in perioperative CRP, hs-cTnT, and CPK-MB levels) [15,25–27] was not confirmed in the PROFACE trial. Because of no significant differences in the clinical preoperative or
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Age at initiation of amiodarone therapy hypertension baselin
2019-04-18
Age at microcystin lr of amiodarone therapy, hypertension, baseline free T4 level, and age at the end of follow-up were evaluated as candidate predictors of amiodarone-induced hyperthyroidism. In order to test this hypothesis, a stepwise multivariate logistic regression analysis was performed. Conse
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La descripci n de la batalla de
2019-04-18
La descripción de la batalla de Churubusco obtiene un grado mayor de dramatismo en el tiempo presente, índice de un tiempo congelado, eternizado en un momento histórico, aunque no en sitio sino desde el punto de vista de Juan Bolao (“que subía al mirador”) desde la Quinta de San Jacinto, lugar campe
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br Materials and methods br Results br Discussion To our
2019-04-17
Materials and methods Results Discussion To our best knowledge, a multi-modality approach to systematically characterize an OS in vivo orthotopic model, using an aggressive OS cell line has not been previously reported. The advantage of using multi-modality approach i.e. BLI, histopathology
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Poor knowledge among caretakers of how to work
2019-04-17
Poor knowledge among caretakers of how to work with disability-related disorders could also be an issue. For example, poor knowledge of how to correctly position a child with severe cerebral palsy could lead to inadequate feeding; at worst, these efforts can cause aspiration and even death. Social a
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Three possible mechanisms may underlie the decrease in the
2019-04-17
Three possible mechanisms may underlie the decrease in the number of PVBs in the present patient: the first is the antiarrhythmic action of Omacor, the second is the natural time course of PVBs, and the third is the day-to-day variability in the number of PVBs. Therefore, we performed an additional
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pterostilbene In the s several hospital based surveys
2019-04-17
In the 1990s, several hospital-based surveys were reported. In a survey of AF among 2686 acute medical admissions to a district general hospital in Glasgow, UK [4], the prevalence of AF was 6.3%, with the predominant associated medical conditions being ischemic heart disease, hypertension, and valvu
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All patients with rickettsial infections reported
2019-04-17
All patients with rickettsial infections reported by Dittrich and colleagues presented with fever at admission, and few patients presented with typical eschars of inoculation (only 3·6% of patients with murine typhus and 6·7% with scrub typhus). This finding might be a result of poor awareness about
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