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Although these studies demonstrated the efficacy
2019-04-16
Although these studies demonstrated the efficacy of pacemaker treatment for preventing or reducing VVS, all 3 trials were retrospective and uncontrolled [10]. Therefore, RCTs of cardiac pacing in VVS were proposed in the late 1990s. The era of RCTs: is pacemaker efficacy due to a placebo effect?
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Programmed death ligand PD L
2019-04-16
Programmed death ligand 1 (PD-L1) expression is a characteristic feature of EBV-associated malignancies. Research has shown that an increase of PD-1-expressing intratumoral CD8 T cells predicts a poor prognosis for nasopharyngeal carcinoma. Preliminary data from a phase Ib study, KEYNOTE-028, showed
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Another widely used tool is the Brief Pain Inventory BPI
2019-04-16
Another widely used tool is the Brief Pain Inventory (BPI), developed by Cleeland and Ryan. The BPI is a questionnaire used to determine overall pain intensity and functional interference as a result of pain. Specifically, it BAY 87-2243 examines functional interference in terms of general activity
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br The Global Burden of
2019-04-16
The Global Burden of Disease Study notes a substantial decrease in long-established global health threats such as communicable diseases and malnutrition, while underscoring the rise in non-communicable diseases and years lived with potentially disabling illnesses and injuries. One important but la
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br Stephanie Topp points to the limitations of quality measu
2019-04-16
Stephanie Topp points to the limitations of quality measurement in Commission on High Quality Health Systems (HQSS Commission; May, 2017) that might not fit the real-world contexts of low-income and middle-income countries (LMICs). She also takes issue with a narrow set of generic indicators and t
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HBV DNA levels are associated with clinically significant pa
2019-04-16
HBV DNA levels are associated with clinically significant pathological events, such as cirrhosis; therefore, changes in the serum levels of HBV DNA could determine a risk for hepatocellular carcinoma. For on-treatment follow-up, HBeAg loss/seroconversion is important during the nucleoside therapy fo
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Different ideas however emerged in the s and s
2019-04-16
Different ideas, however, emerged in the 1960s and 1970s in the minds of computational biologists interested in the theory of wave propagation in excitable media. Based on chemical [17] and numerical experiments, [18] scientists in the Soviet Union and the USA began to suggest that fibrillation was
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Aunque m s por afinidad electiva que
2019-04-16
Aunque más por afinidad electiva que por propia decisión del autor, lo cierto es que justamente ese conjunto de rasgos aproximaría la obra al llamado libro de artista, modalidad creativa tan característicamente vanguardista como la simulación crítica, la interdisciplinariedad, el collage, el disposi
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FPET is a valuable tool to support
2019-04-15
FPET is a valuable tool to support monitoring of SDG 3·7, which calls for universal access to family planning by 2030, albeit with a focus on demand and utilisation rather than access. Nonetheless, subnational geographic projections must be considered in light of some data limitations. Unmarried wom
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Polysaccharides fatty acid esters glycosides iridoids anthra
2019-04-15
Polysaccharides, fatty old town esters, glycosides, iridoids, anthraquinones, flavonoids, phytosterols, carotenoids, vitamin A, antraquinones, potassium, and others have been identified as putative active ingredients in NJ. Our previous report indicated that gentisic, p-hydroxybenoic, and chlorogen
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The standard therapy for chordoma is excision Local recurren
2019-04-15
The standard therapy for chordoma is excision. Local recurrence, but not metastasis, is a major determinant of prognosis. Because local recurrence is related to initial surgical margin and intra-operative tumor cell contamination, achieving a safe margin is very important. Boriani [6] reported 153 c
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br Therapy for the CPVT br Conflict of interest br
2019-04-15
Therapy for the CPVT Conflict of interest Acknowledgment This work was supported by Health Science Research grant from the Ministry of Health, Labour and Welfare of Japan for Clinical Research on Measures for Intractable Diseases (2016-032). Introduction Bradyarrhythmia is a serious ele
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In the context of cataract surgery Nathan Congdon
2019-04-15
In the context of cataract surgery, Nathan Congdon and colleagues (August, p e37) propose the possibility of using early postoperative assessment of all patients or late assessment only of those who return for follow-up without additional prompting as practicable methods to improve long-term patient
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The greater relative importance of indirect causes could be
2019-04-15
The greater relative importance of indirect causes could be a result of successful addressing of direct complications of pregnancy and childbirth, and of a change in risk factors and disease patterns. Indirect causes of death include the effects of pre-existing disorders, such as HIV infection, ment
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Si los sicarios y sus
2019-04-15
Si los sicarios y sus cárteles ejercen un oficio de tinieblas, donde “madrugar” es uno de los ejes rectores de un México violento, zafio, “kafkiano” y pulsante de impunidad, para Juan Villoro: Circunscrito por el crimen, la miseria y la muerte, el tema de una juventud cercada por la violencia es t
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