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As the proposed infrastructure has three layers see Fig
2020-07-29
As the proposed infrastructure has three layers (see Fig. 11), firstly, we evaluated the times measured in (A), (B), and (C), as shows Fig. 15. The time obtained in (A) is the execution time of the functions implemented in the independent layer server (COScore). Then, the time in (B) is derived from
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The hallmark activity of endothelin is potent constriction o
2020-07-29
The hallmark activity of endothelin-1 is potent constriction of vascular smooth muscle. The putative pathogenic roles that have been suggested for endothelin-1 usually involve a vasoconstrictive component (Opgenorth, 1995). In this regard, we examined the ability of A-216546 to inhibit endothelin-1
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br Experimental Procedures br Results br Discussion Studies
2020-07-28
Experimental Procedures Results Discussion Studies of radioactive neurotransmitter release in dub inhibitor slices have shown to be useful to estimate the effect of dopamine agonists and antagonists on the presynaptic receptors modulating neurotransmitter transmitter release, as well as th
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In this study we examined a possible
2020-07-28
In this study, we examined a possible association between the 19-bp prostaglandin e2 and the 9-bp repeat in the DHFR gene and the risk of spina bifida in 121 mothers of a spina bifida affected child, 292 control women, 109 spina bifida patients and 234 pediatric controls using a case-control design.
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The kinetic characteristics of CPT A and
2020-07-28
The kinetic characteristics of CPT1A and CPT1B, encoded by cpt1a and cpt1b respectively, have been well elucidated in mammals. McGarry and Brown (1997) pointed out that CPT1A possessed a low Km for carnitine (0.03 mM) and CPT1B had a high Km (0.50 mM) for carnitine in rat. In the present study, the
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bay 41 According to the previous experimental investigations
2020-07-28
According to the previous experimental investigations [2,43], the studied ionic liquids shift the P-T equilibrium diagrams of methane hydrate toward higher pressures and lower temperatures, suggesting the inhibitory effects of these bay 41 materials on the equilibrium conditions of methane hydrate
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The Power Distribution Current Limiter was used to power
2020-07-28
The Power Distribution Current Limiter was used to power a load and the Autonomous Current Limiter, which in turn was used to power a load and the Controlled Current Limiter and its load. Everything was controlled by a single FPGA powered separately (due to the Power Distribution Current Limiter) an
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We retrospectively evaluated all adult patients with AML or
2020-07-28
We retrospectively evaluated all adult patients with AML or MDS who received matched related or unrelated allo-HCT at MD Anderson Cancer Center (MDACC) from January 2005 to December 2011 (total: 613 patients; HLA-DPB1 matched: 363 [59%], and HLA-DPB1 mismatched: 250 [41%]). All patients were matched
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br Conclusions CK inhibition protects young and aging WM fun
2020-07-28
Conclusions CK2 inhibition protects young and aging WM function against an ischemic episode by preserving oligodendrocytes and axonal structure by maintaining mitochondrial integrity. CK2 recruits CDK5 and AKT/GSK3ß signaling to mediate WM ischemic injury in a differential spatiotemporal manner s
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Accumulating data show that NPC L exerts
2020-07-28
Accumulating data show that NPC1L1 exerts a proatherogenic effect. For example, in low-density lipoprotein (LDL) receptor (Ldlr) mice with gastrointestinal tract-specific overexpression of NPC1L1, cholesterol feeding markedly promotes intestinal cholesterol gamma-Glu-Cys synthesis and causes hyperc
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After their initial identification in seatrout ovaries mPRs
2020-07-28
After their initial identification in seatrout ovaries [24], mPRs have been identified in several tissues, including the central nervous system. They are expressed both in the depends on and the spinal cord [25], [26], [28], [29] and mPRα expression in glial cells was up-regulated following traumat
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the most successful film In looking at exist http www
2020-07-27
In looking at existing FGE substrates from other organisms, there are no reported effects on conversion efficiency of the general XCXPXRX pattern with respect to placement within or at the N′ or C′ terminus of polypeptides, and it has been suggested that the aldehyde formation is independent of the
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While both T bet and IRF are
2020-07-27
While both T-bet and IRF4 are rapidly induced in response to CD3 and CD28 stimulation (Figure 1D), enhanced IFN-γ EHNA hydrochloride australia by IRF4 inhibition was not due to increased T-bet expression. T-bet overexpression by HDV transfection also did not affect IRF4 expression (data not shown).
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br Materials and methods br Results
2020-07-27
Materials and methods Results Discussion The role of pro-inflammatory pathways linked to the ubiquitin-proteasome system in the pathogenesis of atherosclerosis is an emerging area of investigation. Indeed, studies demonstrate putative roles of proteasomal blockade, protective effects of ubi
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Nevertheless the evidence for a
2020-07-27
Nevertheless, the evidence for a role of DDR1 in experimentally-induced renal disease is not uniquely restricted to the glomerular compartment. The Paris-based group of Chatziantoniou and Dussaule explored the role of DDR1 in renal inflammation and fibrosis related to primitive tubule-interstitial i
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