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Since ET was discovered first and showed
2020-07-09
Since ET-1 was discovered first and showed a wide variety of actions not only on the cardiovascular system but also on various other tissues, much information has accumulated on ET-1 compared with the two other peptides. The method for measurement of ET-1 levels in plasma or various tissues by means
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Introduction With an annual world production of
2020-07-09
Introduction With an annual world production of around 750 million tons, wheat is grown on more agricultural area than any other food crop and is the main source of plant protein in human nutrition [1,2]. Wheat is composed of 8–15% protein, from which 85–90% is gluten [3]. The unique viscoelastic a
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br DDR receptor and MMP expression Type
2020-07-09
DDR2 receptor and MMP-13 expression Type II collagen protein in articular cartilage is highly stable structure as its half-life is 117 years [43]. The chondrocytes have limited ability to synthesis type II collagen protein in the matrix of mature articular cartilage once the collagen gets disrupt
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br Results br Discussion The origin
2020-07-09
Results Discussion The origin and fate of Tfh cells has been intensely studied since their first description 14 years ago (Breitfeld et al., 2000, Schaerli et al., 2000). Although mice engineered to report BCL6 (Kitano et al., 2011, Liu et al., 2012) and interleukin-21 (IL-21) (Lüthje et al.,
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BQ-788 sodium salt Haj Yahya et al applied native chemical
2020-07-09
Haj-Yahya et al. [52] applied native chemical ligation for the construction of diubiquitin probes. They attached a cysteine residue to the lysine side chain of the proximal ubiquitin and ligated the distal module using the C-terminal thioester of ubiquitin. Elimination of the sulfur BQ-788 sodium sa
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Phosphatase Inhibitor Cocktail (2 Tubes, 100X) To ascertain
2020-07-09
To ascertain separation of the distinct enzymatic activities found in this protein preparation following separation on the HAP column, a rigorous quantitative analysis was conducted on the nickel–agarose elution and HAP FT pools of protein. For these analyses, each pool of protein was dialyzed in th
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In attempts to further purify His
2020-07-09
In attempts to further purify [His]6-Artemis, numerous matrices were assessed including anion and cation exchange, and Tranilast australia interaction chromatography. The results from these matrices were universally poor (data not shown). Fractionation via adsorption chromatography on a hydroxyapati
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Sp family protein has been regarded as
2020-07-09
Sp family protein has been regarded as the housekeeping gene and is ubiquitously expressed. Although Sp family expression is regulated with some stimuli [17], [20], the total Sp family protein levels are not changed in most cases, as observed in our present study (Fig. 4). Constitutive binding of th
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Introduction Psoralea corylifolia L Leguminosae is a
2020-07-09
Introduction Psoralea corylifolia L. (Leguminosae) is a well-known traditional Chinese medicine, and it has been widely used for the treatment of various diseases like bronchial asthma, leucopenia, vitiligo and psoriasis in East Asian countries (Zhang et al., 1990). Previous studies have reported t
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E cadherin is an adhesive Ca dependent transmembrane protein
2020-07-09
E-cadherin is an adhesive Ca2+ dependent transmembrane protein mediating tight and strong cell-cell adhesion through homophilic interactions. There is strong evidence in favour of the major role of E-cadherin in melanocytes adhesion to keratinocytes in the THZ1 Hydrochloride (Tang et al., 1994). Th
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br Conclusions br ISG is an ubiquitin like protein
2020-07-08
Conclusions ISG15 is an ubiquitin‐like protein that is induced by treating mammalian IC261 sale with interferon‐α/β. UbE1L was identified as the E1‐activating enzyme for ISG15 in the course of experiments that demonstrated that the nonstructural or NS1 protein of influenza B virus inhibits ISG
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br Development of the double strand break
2020-07-08
Development of the double strand break repair model for meiotic recombination Meiotic recombination was first described by Frans Alfons Janssens using InstaBlue Protein Stain Solution in the salamander Batracoseps attenuatus in 1909 [21] and then further elaborated at the genetic level in Drosop
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br The DDR kinase domain The DDR
2020-07-08
The DDR1 kinase domain The DDR1 intracellular kinase domain shares the typical structure of other kinase domains (Fig. 1). However, how DDR1 kinase is activated upon collagen binding is poorly understood. It is thought that the process is fundamentally different from the accepted paradigm of liga
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br Materials and methods br Results br Discussion NB
2020-07-08
Materials and methods Results Discussion NB has been shown to induce cancers in many tissues including the kidney, liver, and thyroid, following chronic inhalation in animals (Hsu et al., 2007). The available data indicate that a lager majority of studies on NB evaluate the effects of toxic
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Introduction Cytochrome P CYP A
2020-07-08
Introduction Cytochrome P450 (CYP)3A is the most important enzyme involved in the metabolism of 30–40% of currently prescribed drugs [1]. The Cilomilast level and activity of CYP3A show large intra- and inter-individual variability, which contributes to unpredictable drug response and toxicity. A
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