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Immature and mature B cells adapt differently to signal
2019-07-02
Immature and mature Isochlorogenic acid C adapt differently to signal transduction via BCR [2]. This functional dichotomy is also regulated by noncytokine substances in the surroundings of mature and immature B lymphocytes, such as the prostanoid family of lipid mediators including PGD2, PGE2, PGF2
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As a support chitosan presents interesting characteristics t
2019-07-02
As a support, chitosan presents interesting characteristics that reinforce its great potential for enzyme immobilization [18,19]. Firstly, it is produced from renewable natural sources in addition to being biodegradable and water insoluble [20,21]. Also, the main peculiarity in the chitosan structur
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Kinetic isotope effects KIEs inform on bond vibrational chan
2019-07-02
Kinetic isotope effects (KIEs) inform on bond vibrational changes between the ground state (GS) and TS of a chemical reaction and remain one of the most powerful experimental techniques for interrogating TS structure. KIEs on enzyme reactions measured by the internal LY-411575 of labeled substrates
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br Asb Proteins and Mitochondrial Function Mitochondria are
2019-07-02
Asb Proteins and Mitochondrial Function Mitochondria are intracellular organelles in eukaryotic AR-42 inhibitor structure and are the main sites of oxidative phosphorylation and ATP production. In addition, mitochondria serve as signal transduction docking stations in pyroptosis and regulate a p
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The collagen field undoubtedly regains attractiveness with t
2019-07-01
The collagen field undoubtedly regains attractiveness with the emergence of new concepts (cell niche, regulation of growth factor bioavailability, mechanotransduction, cell microenvironment sensing) and new tools to investigate their in vivo functions (atomic force microscopy (AFM), second harmonic
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We observed the IVM potentiation of currents induced by the
2019-07-01
We observed the IVM potentiation of currents induced by the EC5 of Glu or GABA and the IVM inhibition of currents induced by the EC90 of Glu or GABA in wild-type GluCls and GABACls. The EC50 of IVM for the potentiation in GluCls was 3.5-fold smaller than that in GABACls (Fig. 4, Fig. 8B, Table 2), a
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br Introduction Incidence of oral cancers
2019-07-01
Introduction Incidence of oral cancers accounts for ∼3% of all malignancies. Oral squamous cell carcinoma (OSCC) accounts for >95% of all malignancies in the oral cavity, and it is the fifth leading cause of cancer death in the male population in Taiwan. OSCC is treated mainly with surgery. Post
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br Material and methods br
2019-07-01
Material and methods Results Discussion ES-SCLC is a disease with poor prognosis. Treatment outcome has not improved significantly during the last decades despite great efforts have been made. Maintenance therapy has been tried in several clinical trials with the aim to prevent the onset of
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In patients with typical atrial
2019-07-01
In patients with typical atrial flutter circulating around the tricuspid valve, the verification of a bidirectional conduction block is recommended for cavotricuspid isthmus (CTI) ablation, because a unidirectional conduction block at the CTI has been previously reported to cause recurrence of atria
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In the management of BrS patients it is
2019-07-01
In the management of BrS patients, it is important to avoid or treat certain drugs or circumstances such as a febrile state, electrolyte disturbances (hyperkalemia and hypercalcemia), and the use of class Ia/Ic antiarrhythmic drugs, vagotonic agents, beta-adrenergic antagonists, tricyclic antidepres
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Introduction Implantable cardioverter defibrillators ICD car
2019-07-01
Introduction Implantable cardioverter-defibrillators (ICD), cardiac resynchronization therapy defibrillators (CRT-D), and cardiac resynchronization therapy (CRT-P) are useful tools for improving the prognosis and/or sudden cardiac death event rate in patients with heart failure and/or fatal ventric
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In the American College of Chest Physicians provided
2019-07-01
In 2013, the American College of Chest Physicians provided a guideline to the preoperative physiological assessment of patients being considered for surgical resection of lung cancer. It has been recommended that patients must be assessed by a multidisciplinary team before operation, regardless of a
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HET0016 The tumor microenvironment is enriched with EMVs tha
2019-07-01
The tumor microenvironment is enriched with EMVs that are derived not only by proliferating tumor cells, but also from infiltrating macrophages and neutrophils, and support tumor cell survival, growth, invasion and metastasis. Tumor derived EMVs also have the potential to modulate surrounding stroma
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ER provides the clinician with a rapid and
2019-07-01
ER-2000® provides the clinician with a rapid and accurate assessment of a patient׳s arrhythmia, improving clinical decision making and clinical outcomes. Further large-scale study is warranted to confirm the accuracy of ER-2000®. Furthermore, the efficacy and usefulness of ER-2000® should be examine
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br Luego de las iniciales de su nombre G
2019-07-01
Luego de las iniciales de su nombre, G. O., Owen reproduce el fragmento traducido. Por esta afición, no resulta extraño que cuando parte hacia Nueva York, protease inhibitor cocktail mediados de 1928, Owen lleve consigo las Obras completas de Lautréamont. Este, indudablemente, influyó en la confec
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